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欧盟评估非转基因地衣芽孢杆菌菌株T74生产的α-淀粉酶的安全性

放大字体  缩小字体 发布日期:2023-08-03  来源:食品伙伴网  作者:泽夕  浏览次数:61
核心提示:2023年8月2日,欧盟食品安全局就一种α-淀粉酶(α-amylase)的安全性评价发布意见。
   食品伙伴网讯  2023年8月2日,欧盟食品安全局就一种α-淀粉酶(α-amylase)的安全性评价发布意见。
 
  据了解,这种食品酶是由非转基因地衣芽孢杆菌菌株T74生产的,旨在用于八种食品制造过程:生产葡萄糖浆和其他淀粉水解产物的淀粉加工、蒸馏酒精生产、精制糖和未精制糖生产、酿造过程、谷物加工、果汁生产的水果和蔬菜加工、果汁以外产品的水果和蔬菜加工以及乳制品的生产。
 
  经过评估,专家小组认为,在预期的使用条件下(蒸馏酒精生产除外),不能排除饮食暴露引起过敏反应的风险,但这种可能性被认为很低。根据所提供的数据,评估小组得出结论,这种食品酶在预期使用条件下不会引起安全问题。部分原文报道如下:
 
  The food enzyme α-amylase (4-α-D-glucan glucanohydrolase; EC 3.2.1.1) is produced with the non-genetically modified microorganism Bacillus licheniformis strain T74 by Novozymes A/S. The production strain met the qualifications of the qualified presumption of safety (QPS) approach. The food enzyme is intended to be used in eight food manufacturing processes: starch processing for the production of glucose syrups and other starch hydrolysates, distilled alcohol production, refined and unrefined sugar production, brewing processes, cereal-based processes, fruit and vegetable processing for juice production, fruit and vegetable processing for products other than juices and the production of dairy analogues. Since residual amounts of total organic solids (TOS) are removed during two food processes (starch processing for the production of glucose syrups and other starch hydrolysates, distilled alcohol production), dietary exposure was calculated only for the remaining six food manufacturing processes. It was estimated to be up to 0.291 mg TOS/kg body weight per day in European populations. Since the production strain meets the requirements for the QPS approach and no issues of concern arose from the production process of the food enzyme, the Panel considered that toxicological studies were unnecessary. A search for the similarity of the amino acid sequence of the food enzyme to known allergens was made and no match was found. The Panel considered that, under the intended conditions of use, the risk of allergic reactions upon dietary exposure to this food enzyme cannot be excluded (except for distilled alcohol production), but the likelihood is low. based on the data provided, the Panel concluded that this food enzyme does not give rise to safety concerns under the intended conditions of use.
 
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