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欧盟评估扩展使用非转基因赭曲霉菌株AE-P生产的蛋白酶oryzin的安全性

放大字体  缩小字体 发布日期:2024-07-25  来源:食品伙伴网  作者:泽夕  浏览次数:69
核心提示:2024年7月24日,欧盟食品安全局就一种蛋白酶oryzin的安全性评价发布意见。
   食品伙伴网讯  2024年7月24日,欧盟食品安全局就一种蛋白酶oryzin的安全性评价发布意见。
 
  据了解,这种食品酶是由非转基因赭曲霉菌株AE-P生产的,旨在用于8种食品生产过程。
 
  经过评估,专家小组得出结论,这种食品酶在预期使用条件下不会引起安全问题。部分原文报道如下:
 
  The food enzyme oryzin (EC 3.4.21.63) is produced with the non-genetically modified Aspergillus ochraceus strain AE-P by Amano Enzyme Inc. A safety evaluation of this food enzyme was made previously, in which EFSA concluded that this food enzyme did not give rise to safety concerns when used in nine food manufacturing processes. Subsequently, the applicant has requested to extend its use to one additional process, to withdraw two food processes and to revise the use levels. In this assessment, EFSA updated the safety evaluation of this food enzyme when used in a total of eight food manufacturing processes. The dietary exposure to the food enzyme-total organic solids (TOS) was calculated to be up to 0.354 mg TOS/kg body weight (bw) per day in European populations. When combined with the no observed adverse effect level reported in the previous opinion (1862 mg TOS/kg bw per day, the highest dose tested), the Panel derived a margin of exposure of at least 5260. based on the data provided for the previous evaluation and the revised margin of exposure in the present evaluation, the Panel concluded that this food enzyme does not give rise to safety concerns under the revised intended conditions of use.
 
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