关于我们

欧盟评估转基因大肠杆菌菌株K-12 W3110-TKO CDX-088生产的D-阿洛酮糖-3-差向异构酶的安全性

放大字体  缩小字体 发布日期:2025-10-13  来源:食品伙伴网  作者:泽夕  浏览次数:48
核心提示:2025年10月10日,欧盟食品安全局就一种D-阿洛酮糖-3-差向异构酶(d-psicose 3-epimerase)的安全性评价发布意见。
   食品伙伴网讯  2025年10月10日,欧盟食品安全局就一种D-阿洛酮糖-3-差向异构酶(d-psicose 3-epimerase)的安全性评价发布意见。
 
  据了解,这种食品酶是由转基因大肠杆菌菌株K-12 W3110-TKO CDX-088生产的,旨在用于生产特种碳水化合物的糖加工中。
 
  经过评估,专家小组认为,在预期的使用条件下,不能排除饮食暴露引起过敏和诱发反应的风险,但这种情况发生的可能性很低。根据所提供的数据,评估小组得出结论,这种食品酶在预期使用条件下不会引起安全问题。部分原文报道如下:
 
  The food enzyme d-psicose 3-epimerase (EC 5.1.3.30) is produced with the genetically modified Escherichia coli strain K-12 W3110-TKO CDX-088 by Tate & Lyle Ingredients France SAS. The production strain of the food enzyme contains several copies of a known antimicrobial resistance gene. However, based on the absence of viable cells and DNA from the production organism in the food enzyme, this is not considered to be a risk. The food enzyme is intended to be used in the processing of sugars for the production of specialty carbohydrates (d-allulose). Since the Panel considered that residual amounts of food enzyme-total organic solids are removed during the production of d-allulose, dietary exposure was not calculated and toxicological testing was not needed. A search for the homology of the amino acid sequence of the d-psicose 3-epimerase to known allergens was made and no match was found. The Panel considered that a risk of allergic reactions upon dietary exposure to the food enzyme cannot be excluded, but that the likelihood is low. based on the data provided, the Panel concluded that this food enzyme does not give rise to safety concerns under the intended conditions of use.
 
  本文由食品伙伴网食品资讯中心编辑,有任何疑问,请联系news@foodmate.net。
 
 

农业生物技术科普平台

电话:(010)68869850/(0535)6736261

QQ:3112742182

邮箱:media@foodmate.net

鲁公网安备 37060202000936号