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欧盟评估扩展使用非转基因少根根霉菌株AE-TL(B)生产的三酰甘油脂肪酶的安全性

放大字体  缩小字体 发布日期:2025-10-30  来源:食品伙伴网  作者:泽夕  浏览次数:74
核心提示:2025年10月29日,欧盟食品安全局就一种食品酶三酰甘油脂肪酶(triacylglycerol lipase)的安全性评价发布意见。
   食品伙伴网讯  2025年10月29日,欧盟食品安全局就一种食品酶三酰甘油脂肪酶(triacylglycerol lipase)的安全性评价发布意见。
 
  据了解,这种食品酶是由非转基因少根根霉菌株AE-TL(B)生产的,旨在用于5种食品生产过程。
 
  经过评估,专家小组得出结论,这种食品酶在预期使用条件下不会引起安全问题。部分原文报道如下:
 
  The food enzyme triacylglycerol lipase (triacylglycerol acylhydrolase, EC 3.1.1.3) is produced with the non-genetically modified Rhizopus arrhizus strain AE-TL(B) by Amano Enzymes Inc. Two safety evaluations of this food enzyme were made previously, in which EFSA concluded that this food enzyme did not give rise to safety concerns when used in six food manufacturing processes. Subsequently, the applicant has requested to extend its use to the production of 2-palmitic acid-enriched vegetable oil intended for infants aged 0–3 months, to withdraw one food manufacturing process and to revise one use level. In this assessment, EFSA updated the safety evaluation of this food enzyme when used in a total of five food manufacturing processes. Dietary exposure to the food enzyme-total organic solids (TOS) was estimated to be up to 0.33 mg TOS/kg body weight (bw) per day in European populations. When combined with the no observed adverse effect level previously reported (1960 mg TOS/kg bw per day, the highest dose tested), the Panel derived a margin of exposure of at least 5939. based on the new data, the revised margin of exposure and the previous evaluation, the Panel concluded that this food enzyme does not give rise to safety concerns under the revised intended conditions of use.
 
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